[HARMRED] Tar heroin & Oxycontin question

[Dan Bigg]

This looks like a document from Richard Nixon!

Dan

At 11:57 AM -0500 11/9/10, Nabarun Dasgupta wrote:
>Hi Monte,
>
>There were a series of experiments done in the 
>lab before the OxyContin OP was launched to 
>determine if it could be smoked. The basic 
>results were that it was very hard to smoke, 
>even after crushing it. FDA/Purdue redacted much 
>of the details of these experiments before 
>making them public. You can see what's left 
>after the censors here:
>
>http://www.fda.gov/downloads/AdvisoryCommittees/CommitteesMeetingMaterials/Drugs/AnestheticAndLifeSupportDrugsAdvisoryCommittee/UCM183205.pdf
>
>On page 122 of the document, the Purdue 
>scientists conclude that based on their 
>findings, very little of the oxycodone gets out 
>if you try to smoke it. But that is all in the 
>lab. What are people seeing in the real world? 
>Seems to be some success in getting the drugs 
>out based on internet posts, but i don't think 
>it is widespread at this time.
>
>THE MOST SERIOUS PROBLEM WITH THE NEW OXYCONTIN 
>OP is the fear that people will shoot the gunk 
>in an artery. Basically we want to avoid this: 
>you crush the pill, mix it with water, it turns 
>into a gummy gel mess, you suck it into a big 
>bore needle, and shoot it in your femoral 
>artery. This is what happened in the UK when 
>they introduced similar tamper-deterrent 
>formulations -- the result was gangrene, loss of 
>limbs, etc. Very gross. Paper from 1994 is 
>attached. Alice Bell has made some nice 
>pamphlets on this. We need more awareness.
>
>The use of tar instead/because of the 
>tamper-deterrent formulation is something we as 
>a community need to document and tell FDA and 
>the pharmaceutical industry. There are many more 
>of these types of hard to crush formulations 
>coming down the pipeline, and FDA has expressed 
>the desire to see ALL controlled substances be 
>in tamper-deterrent forms. No strong harm 
>reduction or drug user perspective has been 
>involved in all this, sadly. I hope we can find 
>our voice and remind people that "abusers" have 
>a right to health as well.
>
>Nab
>
>
>Content-Disposition: inline;
>	filename*0="Dodd TJ 1994 - Temazepam 
>injection new formulation Scotland	- J "; 
>filename*1="Clin Path.pdf"
>Content-Type: application/pdf; x-unix-mode=0777;
>	name="Dodd TJ 1994 - Temazepam injection 
>new formulation Scotland - J	Clin Path.pdf"
>
>Attachment converted: Poo:Dodd TJ 1994 - 
>Temazepam in.pdf (PDF /«IC») (032368C8)
>
>On Oct 25, 2010, at 4:49 PM, Monte Levine wrote:
>
>>  Does anyone know the approximate ph of west 
>>coast tar heroin? Just how acidic is it?
>>
>>
>>  Have recently heard from one of our younger 
>>folks that the use of tar is increasing due to 
>>the new formulation of Oxycodone, extended 
>>release. Am told that they can't shoot them 
>>anymore. I forgot to ask if they could still be 
>>smoked. Anyone know?
>>
>>
>>  Be well Y'all
>>  monte
>>
>>
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