[HARMRED] HARMRED Digest, Vol 12, Issue 16

[Dan Bigg]

Let's face reality.  The addition of naloxone to an already mixed 
agonist/antagonist was done to allow the Reck-Ben Co. to take two 
generics and justify a astronomical price for them.  I have seen no 
evidence that the naloxone antagonizes more than the bup does inherent 
with its existing nature.

Why would the US need what the rest of the world using bup does not 
need?  The only all-american answer I can see is to allow a pharm 
company to make more money!  That's the US!

Similarly, years ago, the Hepatitis B vaccine (developed with US 
government research $) sat on the shelf for five years once finished to 
allow the pharmaceutical programs to arrange to make massive profits 
from it... (From "The War Against Hepatitis B"by Muraskin).  Again, 
millions of lives were at stake.  Imagine the US commited itself to 
fighting communism by vaccinating the world against HBV instead wagging 
war in Vietnam.  Which would have cast a light on the finest of American 
values -- waging war or saving millions of lives?

What can we learn from these lessons of the past?

Peace, Dan

On 8/10/11 9:42 PM, Robert Heimer wrote:
> However, it must be noted (and this was first noticed in New Zealand and
> confirmed in many locations subsequently) that the level of deterrence
> is actually rather low. Seems most of those against whom the inclusion
> of naloxone is targeted shrug off the inconvenience and annoyance of the
> brief and minor extent of opioid antagonism produced by the naloxone.
>
> Steve Alsum wrote:
>    
>> Naloxone is included with bubrenorphine in suboxone to discourage
>> injection.  When used as directed, suboxone is taken sublingually (under
>> the tongue) and naloxone is not absorbed or is at least less available
>> to the body when taken this way.  If injected then both the
>> buprenorphine and the naloxone will be active in the body.  They put it
>> in to discourage abuse through injection.
>>
>> Subutex is just buprenorphine without naloxone.  It is generally
>> prescribed to pregnant women because they do not know how naloxone will
>> affect the unborn fetus.
>>
>> Steve
>>
>> On 8/9/2011 4:39 PM, harmred-request at drcnet.org wrote:
>>
>>      
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>>> Today's Topics:
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>>>      1. Fwd: FW: CESAR FAX: IDUs More Likely to Use Diverted
>>>         Buprenorphine to Self-Medicate (Irina Alexander)
>>>
>>>
>>> ----------------------------------------------------------------------
>>>
>>> Message: 1
>>> Date: Tue, 9 Aug 2011 16:39:31 -0400
>>> From: Irina Alexander<reformdrugpolicy at gmail.com>
>>> Subject: [HARMRED] Fwd: FW: CESAR FAX: IDUs More Likely to Use
>>> 	Diverted	Buprenorphine to Self-Medicate
>>> To: Harm Reduction Forum<HARMRED at drcnet.org>
>>> Cc: Eric Sterling<esterling at cjpf.org>
>>> Message-ID:
>>> 	<CAKFfvDk5KM+=KkrNpcrf=tE9zRpNL=oWD-vxPekouFxvWGX+6A at mail.gmail.com>
>>> Content-Type: text/plain; charset="iso-8859-1"
>>>
>>> Does anyone know the answer to the question from Eric Sterling below?
>>>
>>> ---------- Forwarded message ----------
>>> From: Eric Sterling<esterling at cjpf.org>
>>> Date: Tue, Aug 9, 2011 at 1:17 PM
>>> Subject: FW: CESAR FAX: IDUs More Likely to Use Diverted Buprenorphine to
>>> Self-Medicate
>>> To: Irina Alexander<reformdrugpolicy at gmail.com>
>>>
>>>
>>> ****
>>>
>>> Can someone explain the role of naloxone in the buprenorphine/naloxone
>>> combination?
>>>
>>> E****
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>>> *From:* Cesar cesar [mailto:cesar at cesar.umd.edu]
>>> *Sent:* Monday, August 08, 2011 5:04 PM
>>> *To:* esterling at cjpf.org
>>> *Subject:* CESAR FAX: IDUs More Likely to Use Diverted Buprenorphine to
>>> Self-Medicate****
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>>>        
>>
>>
>>      
>    

-- 
Dan Bigg, Director                        cra at attglobal.net
Chicago Recovery Alliance             www.anypositivechange.org
3110 W Taylor St                        voice 1-312-953-3797
Chicago IL  60612                        fax 1-773-489-7448